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fluorescent probes 2

hydrogen sulfide 2

probe 2

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Fluorescent probes and functional materials for biomedical applications

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 10,   Pages 1425-1437 doi: 10.1007/s11705-022-2163-1

Abstract: Due to their simplicity in preparation, sensitivity and selectivity, fluorescent probes have become theIn addition, many long-wavelength fluorescent probes developed have also proven applicable for inHere, we highlight examples of fluorescent probes and functional materials for biological applicationsselected from the special issues “Fluorescent Probes” and “Molecular Sensors and Logic Gates” recently

Keywords： fluorescent probes     imaging     cell     biomedicine     biomolecules    

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Recent advances of small-molecule fluorescent probes for detecting biological hydrogen sulfide

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 34-63 doi: 10.1007/s11705-021-2050-1

Abstract: the study of H2S in subcellular organelles, facilitated by the development of fluorescent probesThe probes reviewed in this paper were categorized according to their chemical mechanism of sensing andprobes, and metal sulfide precipitation-based probes.The structure of the probes, their sensing mechanism, and imaging results have been discussed in detailMoreover, we also introduced some probes for hydrogen polysulfides.

Keywords： hydrogen sulfide     fluorescent probe     reducibility     nucleophilicity     copper sulfide precipitate     hydrogen polysulfides    

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Special issue on “Fluorescent probes”

Adam C. Sedgwick, Tony D. James

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 1,   Pages 1-3 doi: 10.1007/s11705-019-1910-4

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Recent advances in small molecule fluorescent probes for simultaneous imaging of two bioactive molecules

Yongqing Zhou, Xin Wang, Wei Zhang, Bo Tang, Ping Li

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 4-33 doi: 10.1007/s11705-021-2041-2

Abstract: Fluorescence imaging associated with small molecular probes has been widely used in the imaging of bioactiveSingle organic molecule fluorescent probes have been successively developed to simultaneously monitorsummarizing the design strategies, classifications, and bioimaging applications of dual-response fluorescent probes

Keywords： bioactive molecules     fluorescent probes     in living cells and in vivo     review    

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Design and use of group-specific primers and probes for real-time quantitative PCR

Juntaek LIM, Seung Gu SHIN, Seungyong LEE, Seokhwan HWANG

Frontiers of Environmental Science & Engineering 2011, Volume 5, Issue 1,   Pages 28-39 doi: 10.1007/s11783-011-0302-x

Abstract: paper is intended to provide guidelines and general principles for designing group-specific primers and probesanaerobic processes and biologic nutrient removal processes. qPCR assays using group-specific primers and probes

Keywords： absolute quantification     design guideline     primer     probe     real-time quantitative polymerase chain reaction (qPCR)    

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Near-infrared benzodiazoles as small molecule environmentally-sensitive fluorophores

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 128-135 doi: 10.1007/s11705-021-2080-8

Abstract: The development of fluorophores emitting in the near-infrared spectral window has gained increased attention given their suitable features for biological imaging. In this work, we have optimised a general and straightforward synthetic approach to prepare a small library of near-infrared-emitting C-bridged nitrobenzodiazoles using commercial precursors. C-bridged benzodiazoles have low molecular weight and neutral character as important features that are not common in most near-infrared dyes. We have investigated their fluorescence response in the presence of a wide array of 60 different biomolecules and identified compound 3i as a potential chemosensor to discriminate between Fe2+ and Fe3+ ions in aqueous media.

Keywords： fluorescence     probes     iron     screening     library    

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N-Positive ion activated rapid addition and mitochondrial targeting ratiometric fluorescent probes

Yan Shi, Fangjun Huo, Yongkang Yue, Caixia Yin

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 64-71 doi: 10.1007/s11705-021-2048-8

Abstract: Heterocyclic compound quinoline and its derivatives exist in natural compounds and have a broad spectrum of biological activity. They play an important role in the design of new structural entities for medical applications. Similarly, indoles and their derivatives are found widely in nature. Amino acids, alkaloids and auxin are all derivatives of indoles, as are dyes, and their condensation with aldehydes makes it easy to construct reaction sites for nucleophilic addition agents. In this work, we combine these two groups organically to construct a rapid response site (within 30 s) for H S, and at the same time, a ratiometric fluorescence response is presented throughout the process of H S detection. As such, the lower detection limit can reach 55.7 nmol/L for H S. In addition, cell imaging shows that this probe can be used for the mitochondrial targeted detection of endogenous and exogenous H S. Finally, this probe application was verified by imaging H S in nude mice.

Keywords： heterocyclic compound     hydrogen sulfide     ratiometric     mitochondrial targeted    

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Probes and nano-delivery systems targeting NAD(P)H:quinone oxidoreductase 1: a mini-review

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 2,   Pages 123-138 doi: 10.1007/s11705-022-2194-7

Abstract: Because it is a quinone reductase, many bioimaging probes based on quinone structures target NAD(P)H:This mini-review summarizes quinone-based fluorescent, near-infrared and two-photon fluorescent probesThis review provides valuable information for the future development of probes and nano-delivery systems

Keywords： NAD(P)H:quinone oxidoreductase 1     cancer therapy     target     probe     nanosystem    

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The Development of 3D Atomic Force Microscopy with Magnetically Driven-orthogonal Cantilever Probes Article

Hao Zhang, Junyuan Geng, Haibo Gao, Weibin Rong, Hui Xie

Engineering 2023, Volume 24, Issue 5,   Pages 84-93 doi: 10.1016/j.eng.2022.06.010

Abstract: three-dimensional (3D)-atomic force microscopy (AFM) method based on magnetically driven (MD)-orthogonal cantilever probes

Keywords： 3D-AFM     MD-OCP     Critical dimensions (CDs)     360° Characterization     3D topography reconstruction    

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Title Author Date Type Operation

Fluorescent probes and functional materials for biomedical applications

Journal Article

Recent advances of small-molecule fluorescent probes for detecting biological hydrogen sulfide

Journal Article

Special issue on “Fluorescent probes”

Adam C. Sedgwick, Tony D. James

Journal Article

Recent advances in small molecule fluorescent probes for simultaneous imaging of two bioactive molecules

Yongqing Zhou, Xin Wang, Wei Zhang, Bo Tang, Ping Li

Journal Article

Design and use of group-specific primers and probes for real-time quantitative PCR

Juntaek LIM, Seung Gu SHIN, Seungyong LEE, Seokhwan HWANG

Journal Article

Near-infrared benzodiazoles as small molecule environmentally-sensitive fluorophores

Journal Article

N-Positive ion activated rapid addition and mitochondrial targeting ratiometric fluorescent probes

Yan Shi, Fangjun Huo, Yongkang Yue, Caixia Yin

Journal Article

Probes and nano-delivery systems targeting NAD(P)H:quinone oxidoreductase 1: a mini-review

Journal Article

The Development of 3D Atomic Force Microscopy with Magnetically Driven-orthogonal Cantilever Probes

Hao Zhang, Junyuan Geng, Haibo Gao, Weibin Rong, Hui Xie

Journal Article